反应详情

温度

25 °C

To erucyl alcohol (2) (101.5 g, 310.8 mmol) in 200 ml of toluene was added chloroacetyl chloride (38.6 g, 341.9 mmol). The reaction mixture was stirred at 25° C. for 3 hours. The reaction mixture was then washed with water (100 ml) and the aqueous and organic layers separated The organic layer was dried over sodium sulphate and the solvent removed in vacuo to yield erucyl 2-chloroacetate (3) (118.7 g, 94.3%).

1. washThe reaction mixture was then washed with water (100 ml)
2. customthe aqueous and organic layers separated The organic layer
3. dry with materialwas dried over sodium sulphate
4. customthe solvent removed in vacuo