HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Bromide → 2-Propoxybenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Bromide | HCID 6332 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Hydroxybenzonitrile | HCID 11907 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 2-Propoxybenzonitrile | HCID 2760470 | — |
Reaction Steps
75 g (630 ml) of 2-hydroxybenzonitrile are refluxed with 174 g (1.26 mol) of potassium carbonate and 232.2 g (1.89 mol) of ethyl bromide in 11 of acetone overnight. The solid is filtered off, the solvent is removed under reduced pressure and the residue is distilled under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07704999B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-ea7015aecf944501a8a2dabf2399f7d4 |
| Source note | uspto-grants-2010_04 |