Tetrabutylammonium Fluoride → HCID 86618187, compound

Participants

Reaction Steps

To a solution of intermediate (21) (0.14 mmol) in THF (4 mL) was added n-Bu4NF (1 M solution in THF; 2.1 mL, 2.1 mmol). The reaction mixture was stirred at room temperature for 12 hours and then loaded onto a silica gel column. The reaction product was eluted (n-pentane/Me2CO) and further purified by HPLC over silica to afford 0.0035 g, (44% yield) of the desired product (22) which was characterized as follows:

Provenance & Evidence