2-Methyl-5-hydroxypyridine → HCID 62074621, compound
Reaction equation
[OH:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:8])=[N:6][CH:7]=1.F[C:10]1[N:17]=[CH:16][CH:15]=[CH:14][C:11]=1[C:12]#[N:13]>>[CH3:8][C:5]1[N:6]=[CH:7][C:2]([O:1][C:10]2[N:17]=[CH:16][CH:15]=[CH:14][C:11]=2[C:12]#[N:13])=[CH:3][CH:4]=1Participants
3
Procedure
5-hydroxy-2-methylpyridine and 2-fluoronicotinonitrile were processed according to the method of Example 128B to provide the product. MS (ESI+) m/z 212 (M+H)+;
Workup
- customto provide the product
Sources & evidence
- ORD record
- ord-574e468c2baa4aa58ce1b438736ff472
- Source dataset
- uspto-grants-2010_04
- Patent number
- US07704997B1
Reaction notes
Loading…