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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 645546Generated: October 26, 2026

3-Piperidinol, 1-methyl- → 2-(1-Methyl-piperidin-3-yloxy)-nicotinonitrile

https://huagongshe.com/reaction/645546

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Piperidinol, 1-methyl-HCID 98016—
Reactant3-Cyano-2-fluoropyridineHCID 2783254—
Product2-(1-Methyl-piperidin-3-yloxy)-nicotinonitrileHCID 68582686—

Reaction Steps

2-Fluoro-nicotinonitrile was reacted with 1-methyl-piperidin-3-ol according to the method of Example 85A to provide the title compound. MS (DCI/NH3) m/z 218 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07704997B1
Source datasetuspto-grants-2010_04
ORD IDord-43dbebaf80b24c09824e8d2b508845a8
Source noteuspto-grants-2010_04