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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 645563Generated: October 30, 2026

1,1,1-Trifluoro-2-iodoethane → 1-Bromo-4-fluoro-2-(2,2,2-trifluoroethoxy)benzene

https://huagongshe.com/reaction/645563

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1,1-Trifluoro-2-iodoethaneHCID 67709—
Reactant2-Bromo-5-fluorophenolHCID 2724600—
Product1-Bromo-4-fluoro-2-(2,2,2-trifluoroethoxy)benzeneHCID 57984511—

Reaction Steps

2-Bromo-5-fluoro-phenol was reacted with 1,1,1-trifluoro-2-iodo-ethane according to the method of Example 108A to provide the title compound. MS (DCI/NH3) m/z 273 (M)+, 275 (M+2)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07704997B1
Source datasetuspto-grants-2010_04
ORD IDord-4b1e65bf01d446539dbcdae56f80dcff
Source noteuspto-grants-2010_04