Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 645647Generated: October 25, 2026

2,3-Bis(trifluoromethyl)aniline → 1-(2,3-Bis(trifluoromethyl)phenyl)-3-(2-fluoropyridin-3-ylmethyl)thiourea

https://huagongshe.com/reaction/645647

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Bis(trifluoromethyl)anilineHCID 19980662—
Reactant(2-Fluoropyridin-3-yl)methanamineHCID 45079719—
Reactant2,3-Dichloro-1-fluorophenylisothiocyanateHCID 86603533—
Product1-(2,3-Bis(trifluoromethyl)phenyl)-3-(2-fluoropyridin-3-ylmethyl)thioureaHCID 8660353290%

Reaction Steps

Prepared in 90% yield from the product of Example 197A and the product of Example 193C according to the procedure described for the product of Example 192D and Example 192G.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07704997B1
Source datasetuspto-grants-2010_04
ORD IDord-90628c7d1c2e4a5499ebdc1f2f802320
Source noteuspto-grants-2010_04