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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 645664Generated: October 26, 2026

2-Fluorobenzonitrile → 2-[(1-Methylpiperidin-3-yl)oxy]benzonitrile

https://huagongshe.com/reaction/645664

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluorobenzonitrileHCID 67855—
Reactant3-Piperidinol, 1-methyl-HCID 98016—
Product2-[(1-Methylpiperidin-3-yl)oxy]benzonitrileHCID 68583720—

Reaction Steps

2-Fluoro-benzonitrile was reacted with 1-methyl-piperidin-3-ol according to the method of Example 85A to provide the title compound. MS (DCI/NH3) m/z 217 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07704997B1
Source datasetuspto-grants-2010_04
ORD IDord-4be03c5a8f274a70b7daf40e34a3d8c1
Source noteuspto-grants-2010_04