Reserpine → HCID 68680671, compound

Participants

Reaction Steps

The title compound was synthesized according to General Procedure 9 using 2-fluoro-5-hydroxypyridine. 1H NMR (DMSO-d6, 400 MHz) δ 7.33 (dd, 1H, J=3.3 Hz, J=8.8 Hz), 7.37 (dd, 1H, J=5.0 Hz, J=7.6 Hz), 8.01 (ddd, 1H, J=3.0 Hz, J=6.7 Hz, J=8.9 Hz), 8.26 (dd, 1H, J=1.6 Hz, J=2.9 Hz), 8.40 (dd, 1H, J=1.9 Hz, J=5.0 Hz), 8.47 (dd, 1H, J=1.9 Hz, J=7.6 Hz); RP-HPLC (Hypersil®-100 C18, 5 μm, 100 Å, 10 cm; 5%-100% acetonitrile-0.1M ammonium acetate over 5 min. 2 mL/min), then 100% acetonitrile isocratic 1 minutes, Rt 3.67 min.

Provenance & Evidence