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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 645846Generated: October 26, 2026

N-{2-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-1,3-thiazol-5-yl}acetamide → n-{5-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)oxy]-2-thienyl}acetamide

https://huagongshe.com/reaction/645846

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-{2-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-1,3-thiazol-5-yl}acetamideHCID 10338403—
Reactant3-Cyclobutyl-7-[(5-nitro-2-thienyl)oxy]-2,3,4,5-tetrahydro-1H-3-benzazepineHCID 10382895—
Productn-{5-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)oxy]-2-thienyl}acetamideHCID 10043835—

Reaction Steps

Example 212 (E212) was prepared from 3-cyclobutyl-7-[(5-nitro-2-thienyl)oxy]-2,3,4,5-tetrahydro-1H-3-benzazepine (E211) using an analogous method to that described for Example 210 (E210); MS (ES+) m/e 357 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07704994B2
Source datasetuspto-grants-2010_04
ORD IDord-d5712c0d60ca4bf3861926d270190186
Source noteuspto-grants-2010_04