2-(p-Bromophenyl)-5-pyrimidinecarboxamidine hydrochloride → 2-(p-Fluorophenyl)-5'-propyl-5,2'-bipyrimidinyl

Participants

Reaction Steps

Example 4 was repeated except that 2-(p-bromophenyl)-5-pyrimidinecarboxamidine hydrochloride and α-pentyl-62 -dimethylaminoacrolein in Example 4 were replaced by 2-(p-fluorophenyl)-5-pyrimidinecarboxamidine hydrochloride and α-propyl-62 -dimethylaminoacrolein, respectively, to obtain 2-(p-fluorophenyl)-5'-propyl-5,2'-bipyrimidinyl, which exhibited a C-N point of 199° C. and a N-I point of 203° C.

Provenance & Evidence