反应详情

A suspension of ethyl 1,2,3,4-tetrahydro-4-(2-hydroxy-5-nitrophenyl)-6-methyl-2-oxo-5-pyrimidine carboxylate (1.00 g, 31.0 mmol) in acetic anhydride (25 mL) was heated to reflux for 2 hours. The reaction mixture was cooled and the excess acetic anhydride was removed in vacuo to afford the desired product as a tan solid which was used in the next reaction without purification.

1. temperaturewas heated
2. temperatureto reflux for 2 hours
3. temperatureThe reaction mixture was cooled
4. customthe excess acetic anhydride was removed in vacuo