HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzaldehyde → N-(2-{2-[(2-hydroxy-3-methyl-4-oxo-3-p-tolyl-cyclobut-1-enyl)-phenyl-methyl]-6-methyl-1H-indol-3-yl}-1,1-dimethyl-ethyl)-acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzaldehyde | HCID 240 | — |
| Edukt | N-[1,1-dimethyl-2-(6-methyl-1H-indol-3-yl)-ethyl]-acetamide | HCID 68580747 | — |
| Edukt | HCID 68581955 | HCID 68581955 | — |
| Produkt | N-(2-{2-[(2-hydroxy-3-methyl-4-oxo-3-p-tolyl-cyclobut-1-enyl)-phenyl-methyl]-6-methyl-1H-indol-3-yl}-1,1-dimethyl-ethyl)-acetamide | HCID 59264919 | — |
Reaktionsschritte
Using general procedure C, 2-methyl-2-p-tolyl-cyclobutane-1,3-dione was reacted with benzaldehyde and N-[1,1-dimethyl-2-(6-methyl-1H-indol-3-yl)-ethyl]-acetamide (from Example 1.2) to give N-(2-{2-[(2-hydroxy-3-methyl-4-oxo-3-p-tolyl-cyclobut-1-enyl)-phenyl-methyl]-6-methyl-1H-indol-3-yl}-1,1-dimethyl-ethyl)-acetamide as a pale yellow solid. MS: 519.5 ([M−H]−).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07705034B2 |
| Quelldatensatz | uspto-grants-2010_04 |
| ORD ID | ord-29c30b223c7a48c3bf20bb935d8b6e1e |
| Quellennotiz | uspto-grants-2010_04 |