Benzaldehyde → N-[2-(2-{[3-(4-chloro-phenyl)-2-hydroxy-3-methyl-4-oxo-cyclobut-1-enyl]-phenyl-methyl}-6-methyl-1H-indol-3-yl)-1,1-dimethyl-ethyl]-acetamide

関与物質

反応手順

Using general procedure C, 2-(4-chloro-phenyl)-2-methyl-cyclobutane-1,3-dione was reacted with benzaldehyde and N-[1,1-dimethyl-2-(6-methyl-1H-indol-3-yl)-ethyl]-acetamide (from Example 1.2) to give N-[2-(2-{[3-(4-chloro-phenyl)-2-hydroxy-3-methyl-4-oxo-cyclobut-1-enyl]-phenyl-methyl}-6-methyl-1H-indol-3-yl)-1,1-dimethyl-ethyl]-acetamide as a pale yellow solid. MS: 539.5 ([M−H]−).

情報源と証拠