HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → 3-Hydroxy-4-methyl-2-[(3-methyl-1H-indol-2-yl)-phenyl-methyl]-4-p-tolyl-cyclobut-2-enone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | Skatole | HCID 6736 | — |
| Reactant | 2-Methyl-2-p-tolyl-cyclobutane-1,3-dione | HCID 68581955 | — |
| Product | 3-Hydroxy-4-methyl-2-[(3-methyl-1H-indol-2-yl)-phenyl-methyl]-4-p-tolyl-cyclobut-2-enone | HCID 25050705 | — |
Reaction Steps
Using general procedure C, 2-methyl-2-p-tolyl-cyclobutane-1,3-dione (from Example 4.1) was reacted with benzaldehyde and 3-methyl-1H-indole to give the title compound as a colorless solid. MS: 406.6 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705034B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-56e8391aa53e486e9e8c92ba97fd8b73 |
| Source note | uspto-grants-2010_04 |