Benzaldehyde → N-{2-[(2-Hydroxy-3-methyl-4-oxo-3-p-tolyl-cyclobut-1-enyl)-phenyl-methyl]-7-methyl-1H-indol-3-ylmethyl}-acetamide

Participants

Reaction Steps

Using general procedure C, 2-methyl-2-p-tolyl-cyclobutane-1,3-dione (from Example 4.1) was reacted with benzaldehyde and N-(7-methyl-1H-indol-3-ylmethyl)-acetamide (prepared from 7-methyl-1H-indole-3-carbaldehyde according to Example 10.1-10.3) to give the title compound as an off-white solid. MS: 477.4 ([M−H]−).

Provenance & Evidence