HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → N-{2-[(2-Hydroxy-3-methyl-4-oxo-3-p-tolyl-cyclobut-1-enyl)-phenyl-methyl]-6-methyl-1H-indol-3-ylmethyl}-N-methyl-formamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | 2-Methyl-2-p-tolyl-cyclobutane-1,3-dione | HCID 68581955 | — |
| Reactant | N-methyl-N-(6-methyl-1H-indol-3-ylmethyl)-formamide | HCID 86619843 | — |
| Product | N-{2-[(2-Hydroxy-3-methyl-4-oxo-3-p-tolyl-cyclobut-1-enyl)-phenyl-methyl]-6-methyl-1H-indol-3-ylmethyl}-N-methyl-formamide | HCID 25050876 | — |
Reaction Steps
Using general procedure C, 2-methyl-2-p-tolyl-cyclobutane-1,3-dione (from Example 4.1) was reacted with benzaldehyde and N-methyl-N-(6-methyl-1H-indol-3-ylmethyl)-formamide to give the title compound as a red solid. MS: 476.6 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705034B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-989f399f45ba44b8b6e7d997b8d8e650 |
| Source note | uspto-grants-2010_04 |