HCID 68579590, compound → 3-Hydroxy-4-methyl-2-[(3-methyl-benzo[b]thiophen-2-yl)-phenyl-methyl]-4-phenyl-cyclobut-2-enone

HRID 646087Notes

Reaction equation

HRID 646087 reaction equation
[CH3:1][C:2]1([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5](=[O:6])[CH2:4][C:3]1=[O:7].[CH3:14][C:15]1[C:16]2[CH:31]=[CH:30][CH:29]=[CH:28][C:17]=2[S:18][C:19]=1[CH:20]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)O>>[OH:6][C:5]1[C:2]([CH3:1])([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:3](=[O:7])[C:4]=1[CH:20]([C:19]1[S:18][C:17]2[CH:28]=[CH:29][CH:30]=[CH:31][C:16]=2[C:15]=1[CH3:14])[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 68579590HCID 68579590, compoundHCID 685810272-Methyl-2-phenyl-cyclobutane-1,3-dione

Product 1

HCID 592649083-Hydroxy-4-methyl-2-[(3-methyl-benzo[b]thiophen-2-yl)-phenyl-methyl]-4-phenyl-cyclobut-2-enone

Procedure

Using general procedure D, 2-methyl-2-phenyl-cyclobutane-1,3-dione (Lit. 1) was reacted with (3-methyl-benzo[b]thiophen-2-yl)-phenyl-methanol to give the title compound as a colorless solid. MS: 409.5 ([M−H]−).

Sources & evidence

ORD record
ord-c377732dc70c4a7bb4c6c59a0a3dfa1d
Source dataset
uspto-grants-2010_04
Patent number
US07705034B2

Reaction notes

Loading…