HuagongsheHuagongshe Chemistry Print Report · For research reference only
(5-Fluoro-3-methyl-benzo[b]thiophen-2-yl)-phenyl-methanol → 2-[(5-Fluoro-3-methyl-benzo[b]thiophen-2-yl)-phenyl-methyl]-3-hydroxy-4-methyl-4-phenyl-cyclobut-2-enone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (5-Fluoro-3-methyl-benzo[b]thiophen-2-yl)-phenyl-methanol | HCID 68579253 | — |
| Reactant | 2-Methyl-2-phenyl-cyclobutane-1,3-dione | HCID 68581027 | — |
| Product | 2-[(5-Fluoro-3-methyl-benzo[b]thiophen-2-yl)-phenyl-methyl]-3-hydroxy-4-methyl-4-phenyl-cyclobut-2-enone | HCID 59264918 | — |
Reaction Steps
Using general procedure D, 2-methyl-2-phenyl-cyclobutane-1,3-dione (Lit. 1) was reacted with (5-fluoro-3-methyl-benzo[b]thiophen-2-yl)-phenyl-methanol to give the title compound as a colorless solid. MS: 427.5 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705034B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-193edf80945747aabd5e50c6126325f7 |
| Source note | uspto-grants-2010_04 |