HCID 68579480, compound → 3-Hydroxy-4-methyl-2-[(5-methyl-benzo[b]thiophen-2-yl)-phenyl-methyl]-4-phenyl-cyclobut-2-enone

HRID 646091Notes

Reaction equation

HRID 646091 reaction equation
[CH3:1][C:2]1([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5](=[O:6])[CH2:4][C:3]1=[O:7].[CH3:14][C:15]1[CH:31]=[CH:30][C:18]2[S:19][C:20]([CH:22]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)O)=[CH:21][C:17]=2[CH:16]=1>>[OH:6][C:5]1[C:2]([CH3:1])([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:3](=[O:7])[C:4]=1[CH:22]([C:20]1[S:19][C:18]2[CH:30]=[CH:31][C:15]([CH3:14])=[CH:16][C:17]=2[CH:21]=1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 68579480HCID 68579480, compoundHCID 685810272-Methyl-2-phenyl-cyclobutane-1,3-dione

Product 1

HCID 592649223-Hydroxy-4-methyl-2-[(5-methyl-benzo[b]thiophen-2-yl)-phenyl-methyl]-4-phenyl-cyclobut-2-enone

Procedure

Using general procedure D, 2-methyl-2-phenyl-cyclobutane-1,3-dione (Lit. 1) was reacted with (5-methyl-benzo[b]thiophen-2-yl)-phenyl-methanol to give the title compound as a colorless solid. MS: 409.3 ([M−H]−).

Sources & evidence

ORD record
ord-fa288872fd3647fd8fb41394c9699188
Source dataset
uspto-grants-2010_04
Patent number
US07705034B2

Reaction notes

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