1-Bromo-4-(propan-2-yloxy)benzene → 1,5-Bis(4-isopropoxyphenyl)indole-2-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][C:11](Br)=[CH:10][CH:9]=2)=[O:5])[CH3:2].[CH:16]([O:19][C:20]1[CH:25]=[CH:24][C:23](B(O)O)=[CH:22][CH:21]=1)([CH3:18])[CH3:17].Br[C:30]1[CH:35]=[CH:34][C:33]([O:36][CH:37]([CH3:39])[CH3:38])=[CH:32][CH:31]=1>>[CH2:1]([O:3][C:4]([C:6]1[N:7]([C:30]2[CH:35]=[CH:34][C:33]([O:36][CH:37]([CH3:39])[CH3:38])=[CH:32][CH:31]=2)[C:8]2[C:13]([CH:14]=1)=[CH:12][C:11]([C:23]1[CH:24]=[CH:25][C:20]([O:19][CH:16]([CH3:18])[CH3:17])=[CH:21][CH:22]=1)=[CH:10][CH:9]=2)=[O:5])[CH3:2]Participants
4
Procedure
The sub-title compound was prepared in accordance with Example 1(b), using 5-bromoindole-2-carboxylic acid ethyl ester, 4-isopropoxyphenylboronic acid and 4-bromo-1-isopropoxybenzene.
Sources & evidence
- ORD record
- ord-d056400c56c74c69add902305923639f
- Source dataset
- uspto-grants-2010_04
- Patent number
- US07705023B2
Reaction notes
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