HCID 68701411, compound → HCID 68696976, compound

Participants

Reaction Steps

A stirred mixture of 1,5-bis(4-isopropoxyphenyl)-4-nitroindole-2-carboxylic acid ethyl ester (335 mg, 0.67 mmol; see Example 4(b)) and Pd/C (10%, 120 mg) in EtOAc was hydrogenated at ambient pressure and temperature for 10 h and filtered through Celite®. The filter cake was washed with EtOAc and the combined filtrates were concentrated and purified by chromatography to yield the sub-title compound (272 mg, 86%).

Provenance & Evidence