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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 646117Generated: October 30, 2026

4-Bromo-2-nitrotoluene → 5-(4-Tert-butylphenyl)-1-(4-methyl-3-nitrophenyl)indole-2-carboxylic acid

https://huagongshe.com/reaction/646117

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-nitrotolueneHCID 123546—
ReactantEthyl 5-(4-(tert-butyl)phenyl)-1H-indole-2-carboxylateHCID 68475095—
Product5-(4-Tert-butylphenyl)-1-(4-methyl-3-nitrophenyl)indole-2-carboxylic acidHCID 68698400—

Reaction Steps

The title compound was prepared in accordance with Example 1 using 5-(4-tert-butylphenyl)indole-2-carboxylic acid ethyl ester and 4-bromo-1-methyl-2-nitrobenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705023B2
Source datasetuspto-grants-2010_04
ORD IDord-4491f1bc8029478eb4a25ff04eebd124
Source noteuspto-grants-2010_04