HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Cyclopentyloxy)pyridine-3-boronic acid → 1-(6-Cyclopentoxypyrid-3-yl)-5-(5-trifluoromethylpyrid-2-yl)-1-H-indole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Cyclopentyloxy)pyridine-3-boronic acid | HCID 57416438 | — |
| Reactant | 5-(5-trifluoromethylpyrid-2-yl)-1H-indole-2-carboxylic acid ethyl ester | HCID 68472386 | — |
| Product | 1-(6-Cyclopentoxypyrid-3-yl)-5-(5-trifluoromethylpyrid-2-yl)-1-H-indole-2-carboxylic acid | HCID 86616823 | — |
Reaction Steps
The title compound was prepared in accordance with Example 36(d) from 5-(5-trifluoromethylpyrid-2-yl)-1H-indole-2-carboxylic acid ethyl ester (see Example 8(b)) and 6-cyclopentoxypyridine-3-boronic acid (see Example 36(c)), followed by ester hydrolysis (see Example 36(e)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705023B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-9c71e72b7a0443dda8a0c9da43d44630 |
| Source note | uspto-grants-2010_04 |