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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 646151Generated: October 28, 2026

1-Bromo-4-cyclopropoxybenzene → 5-(4-tert-Butylphenyl)-1-(4-cyclopropoxyphenyl)-1H-indole-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/646151

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-4-cyclopropoxybenzeneHCID 50998694—
ReactantEthyl 5-(4-(tert-butyl)phenyl)-1H-indole-2-carboxylateHCID 68475095—
Product5-(4-tert-Butylphenyl)-1-(4-cyclopropoxyphenyl)-1H-indole-2-carboxylic acid ethyl esterHCID 68697360—

Reaction Steps

The sub-title compound was prepared in accordance with Example 1(b) from 5-(4-tert-butylphenyl)indole-2-carboxylic acid ethyl ester (see Example 1(a)) and 1-bromo-4-cyclopropoxybenzene (see step (c) above).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705023B2
Source datasetuspto-grants-2010_04
ORD IDord-1911e2ce3b614c8ea623b5329237f8bc
Source noteuspto-grants-2010_04