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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 646154Generated: October 27, 2026

4-Iodobenzonitrile → 5-(4-Cyanophenyl)-1H-indole-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/646154

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-IodobenzonitrileHCID 76467—
ReactantEthyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-2-carboxylateHCID 21111505—
Product5-(4-Cyanophenyl)-1H-indole-2-carboxylic acid ethyl esterHCID 68700480—

Reaction Steps

The sub-title compound was prepared in accordance with Example 8(b) from 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole-2-carboxylic acid ethyl ester (see Example 8(a)) and 4-iodobenzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705023B2
Source datasetuspto-grants-2010_04
ORD IDord-59d78acc96334985b1696dad4bef8c9c
Source noteuspto-grants-2010_04