HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-chloro-1-(4-isopropoxyphenyl)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole-2-carboxylic acid ethyl ester → HCID 68701140, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-chloro-1-(4-isopropoxyphenyl)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole-2-carboxylic acid ethyl ester | HCID 68700431 | — |
| Reactant | 6-Bromo-N-cyclopentylpyridin-3-amine | HCID 72219223 | — |
| Product | HCID 68701140 | HCID 68701140 | — |
Reaction Steps
The title compound was prepared in accordance with Example 8(b) from 3-chloro-1-(4-isopropoxyphenyl)-5-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-1H-indole-2-carboxylic acid ethyl ester (see Example 35, Method 1, step (c)) and 6-bromopyrid-3-ylcyclopentylamine (see Example 45(b)), followed by ester hydrolysis according to Example 35, Method 3, step (b).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705023B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-db4e370ae60d4c15830eab05a7d12c26 |
| Source note | uspto-grants-2010_04 |