HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,4-Dichlorophenyl)boronic acid → 5-(2,4-Dichlorophenyl)-1-(4-isopropoxyphenyl)-1H-indole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,4-Dichlorophenyl)boronic acid | HCID 2734659 | — |
| Reactant | 4-Isopropoxybenzeneboronic acid | HCID 3698726 | — |
| Reactant | ethyl 5-bromo-3-chloro-1H-indole-2-carboxylate | HCID 28330549 | — |
| Product | 5-(2,4-Dichlorophenyl)-1-(4-isopropoxyphenyl)-1H-indole-2-carboxylic acid | HCID 68701175 | — |
Reaction Steps
The title compound was prepared in accordance with Example 54 from 5-bromo-3-chloro-1H-indole-2-carboxylic acid ethyl ester, 2,4-dichlorophenyl boronic acid and 4-isopropoxyphenyl boronic acid, followed by ester hydrolysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705023B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-4c43511e39b344e98dde7b756350e722 |
| Source note | uspto-grants-2010_04 |