Ethyl bromoacetate → HCID 11258842, compound

HRID 646284Notes

Reaction equation

[F:1][C:2]([F:25])([F:24])[O:3][C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11](=[O:23])[C:12]2[CH:13]=[C:14]([CH:18]=[CH:19][C:20]=2[O:21][CH3:22])[C:15]([NH2:17])=[O:16])=[CH:6][CH:5]=1.BrC[C:28]([O:30][CH2:31][CH3:32])=[O:29]>>[CH2:31]([O:30][C:28](=[O:29])[CH2:22][O:21][C:20]1[CH:19]=[CH:18][C:14]([C:15](=[O:16])[NH2:17])=[CH:13][C:12]=1[C:11](=[O:23])[NH:10][C:7]1[CH:8]=[CH:9][C:4]([O:3][C:2]([F:24])([F:25])[F:1])=[CH:5][CH:6]=1)[CH3:32]

Participants

Reactant 2

HCID 7748Ethyl bromoacetate

HCID 11245159HCID 11245159, compound

Product 1

HCID 11258842HCID 11258842, compound

Procedure

The captioned compound was synthesized from 3-N-(4-trifluoromethoxyphenyl)-4-methoxyisophthalamide and ethyl bromoacetate by the same procedure as in the manufacturing method described in Example 1-1-2.

Sources & evidence

ORD record: ord-539eada2457f4b1f9dfad5cbd4467ea3
Source dataset: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07705053B2

Reaction notes

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