2'-Aminoacetophenone → 3-N-(2-acetylphenyl)-4-methoxyisophthalamide

HRID 646306Notes

Reaction equation

[CH3:1][O:2][C:3]1[C:8]([C:9]([OH:11])=O)=[CH:7][C:6]([C:12]([NH2:14])=[O:13])=[CH:5][CH:4]=1.[C:15]([C:18]1[CH:24]=[CH:23][CH:22]=[CH:21][C:19]=1[NH2:20])(=[O:17])[CH3:16]>>[C:15]([C:18]1[CH:24]=[CH:23][CH:22]=[CH:21][C:19]=1[NH:20][C:9](=[O:11])[C:8]1[CH:7]=[C:6]([CH:5]=[CH:4][C:3]=1[O:2][CH3:1])[C:12]([NH2:14])=[O:13])(=[O:17])[CH3:16]

Participants

Reactant 2

HCID 110862'-Aminoacetophenone

HCID 132228085-Carbamoyl-2-methoxybenzoic acid

Product 1

HCID 592651933-N-(2-acetylphenyl)-4-methoxyisophthalamide

Procedure

The captioned compound was synthesized from 6-methoxyisophthalamic acid and 2-acetylaniline by the same procedure as in the manufacturing method described in step C of Example 1-3-1.

Sources & evidence

ORD record: ord-4bf205e1980647339046970dd7019a3c
Source dataset: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07705053B2

Reaction notes

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