2-Chloro-4-fluoro-5-methylaniline → HCID 59265065, compound

HRID 646309Notes

Reaction equation

HRID 646309 reaction equation
[CH3:1][O:2][C:3]1[C:8]([C:9]([OH:11])=O)=[CH:7][C:6]([C:12]([NH2:14])=[O:13])=[CH:5][CH:4]=1.[Cl:15][C:16]1[CH:22]=[C:21]([F:23])[C:20]([CH3:24])=[CH:19][C:17]=1[NH2:18]>>[Cl:15][C:16]1[CH:22]=[C:21]([F:23])[C:20]([CH3:24])=[CH:19][C:17]=1[NH:18][C:9](=[O:11])[C:8]1[CH:7]=[C:6]([CH:5]=[CH:4][C:3]=1[O:2][CH3:1])[C:12]([NH2:14])=[O:13]

Participants

3

Procedure

The captioned compound was synthesized from 6-methoxyisophthalamic acid and 2-chloro-4-fluoro-5-methylaniline by the same procedure as in the manufacturing method described in step C of Example 1-3-1.

Sources & evidence

ORD record
ord-23f3c38b8e0b4a878938347a5f47d8c4
Source dataset
uspto-grants-2010_04
Patent number
US07705053B2

Reaction notes

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