4-(Trifluoromethyl)aniline → HCID 59265109, compound
Reaction equation
[CH3:1][O:2][C:3]1[C:8]([C:9]([OH:11])=O)=[CH:7][C:6]([C:12]([NH2:14])=[O:13])=[CH:5][CH:4]=1.[F:15][C:16]([F:25])([F:24])[C:17]1[CH:23]=[CH:22][C:20]([NH2:21])=[CH:19][CH:18]=1>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:12]([NH2:14])=[O:13])=[CH:7][C:8]=1[C:9]([NH:21][C:20]1[CH:22]=[CH:23][C:17]([C:16]([F:15])([F:24])[F:25])=[CH:18][CH:19]=1)=[O:11]Participants
3
Procedure
The captioned compound was synthesized from 6-methoxyisophthalamic acid and 4-trifluoromethylaniline by the same procedure as in the manufacturing method described in step C of Example 1-3-1.
Sources & evidence
- ORD record
- ord-fe50247c0bad44478b574017a445fb4f
- Source dataset
- uspto-grants-2010_04
- Patent number
- US07705053B2
Reaction notes
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