Cyclopropylamine → 3-[(E)-2-(4-chlorophenyl)-vinyl]-N-cyclopropyl-4-methoxy-benzamide

HRID 646354Notes

Reaction equation

HRID 646354 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=2[O:19][CH3:20])[C:13]([OH:15])=O)=[CH:4][CH:3]=1.[CH:21]1([NH2:24])[CH2:23][CH2:22]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=2[O:19][CH3:20])[C:13]([NH:24][CH:21]2[CH2:23][CH2:22]2)=[O:15])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 69828CyclopropylamineHCID 231413873-[(E)-2-(4-chlorophenyl)vinyl]-4-methoxy-benzoic acid

Product 1

HCID 231415193-[(E)-2-(4-chlorophenyl)-vinyl]-N-cyclopropyl-4-methoxy-benzamide

Procedure

The captioned compound was synthesized from 3-[(E)-2-(4-chlorophenyl)vinyl]-4-methoxy-benzoic acid and cyclopropylamine in accordance with the same procedure as in the manufacturing method described in step C of Example 1-2-3.

Sources & evidence

ORD record
ord-9e4820be670c477b8695fc580c3c4102
Source dataset
uspto-grants-2010_04
Patent number
US07705053B2

Reaction notes

Loading…