Diglycolamine → 3-[(E)-2-(4-chlorophenyl)-vinyl]-N-[2-(2-hydroxyethoxy)-ethyl]-4-methoxy-benzamide

HRID 646356Notes

Reaction equation

HRID 646356 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=2[O:19][CH3:20])[C:13]([OH:15])=O)=[CH:4][CH:3]=1.[NH2:21][CH2:22][CH2:23][O:24][CH2:25][CH2:26][OH:27]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=2[O:19][CH3:20])[C:13]([NH:21][CH2:22][CH2:23][O:24][CH2:25][CH2:26][OH:27])=[O:15])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 13578DiglycolamineHCID 231413873-[(E)-2-(4-chlorophenyl)vinyl]-4-methoxy-benzoic acid

Product 1

HCID 231415163-[(E)-2-(4-chlorophenyl)-vinyl]-N-[2-(2-hydroxyethoxy)-ethyl]-4-methoxy-benzamide

Procedure

The captioned compound was synthesized from 3-[(E)-2-(4-chlorophenyl)vinyl]-4-methoxy-benzoic acid and 2-(2-aminoethoxy)-ethanol in accordance with the same procedure as in the manufacturing method described in step C of Example 1-2-3.

Sources & evidence

ORD record
ord-f767735ffd614e7cab259f50dcd043ff
Source dataset
uspto-grants-2010_04
Patent number
US07705053B2

Reaction notes

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