3-Aminopropionitrile → HCID 23141448, compound

HRID 646363Notes

Reaction equation

HRID 646363 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7](O)=[O:8])=[CH:5][C:4]=1/[CH:12]=[CH:13]/[C:14]1[CH:19]=[CH:18][C:17]([O:20][C:21]([F:24])([F:23])[F:22])=[CH:16][CH:15]=1.[NH2:25][CH2:26][CH2:27][C:28]#[N:29]>>[C:26]([CH2:27][CH2:28][NH:29][C:7](=[O:8])[C:6]1[CH:10]=[CH:11][C:3]([O:2][CH3:1])=[C:4](/[CH:12]=[CH:13]/[C:14]2[CH:15]=[CH:16][C:17]([O:20][C:21]([F:23])([F:22])[F:24])=[CH:18][CH:19]=2)[CH:5]=1)#[N:25]

Participants

3

Reactant 2

HCID 16473-AminopropionitrileHCID 231414984-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acid

Product 1

HCID 23141448HCID 23141448, compound

Procedure

The captioned compound was synthesized from 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acid obtained in step B of Example 2-2-1 and 3-aminopropionitrile in accordance with the same procedure as in the methods described in step C of Example 1-2-3.

Sources & evidence

ORD record
ord-274a8692ff29420fa857902675652deb
Source dataset
uspto-grants-2010_04
Patent number
US07705053B2

Reaction notes

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