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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 646367Generated: October 28, 2026

3-Amino-1,2-propanediol → N-(2,3-dihydroxy-propyl)-4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-benzamide

https://huagongshe.com/reaction/646367

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-1,2-propanediolHCID 73561—
Reactant4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acidHCID 23141498—
ProductN-(2,3-dihydroxy-propyl)-4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-benzamideHCID 23141422—

Reaction Steps

The captioned compound was synthesized from 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acid obtained in step B of Example 2-2-1 and 3-amino-1,2-propanediol in accordance with the same procedure as in the methods described in step C of Example 1-2-3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705053B2
Source datasetuspto-grants-2010_04
ORD IDord-fb1692ac46a041c5bc09dcdaf9d9660e
Source noteuspto-grants-2010_04