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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 646368Generated: October 30, 2026

Serinol → N-(2-hydroxy-1-hydroxymethyl-ethyl)-4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-benzamide

https://huagongshe.com/reaction/646368

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSerinolHCID 68294—
Reactant4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acidHCID 23141498—
ProductN-(2-hydroxy-1-hydroxymethyl-ethyl)-4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-benzamideHCID 23141484—

Reaction Steps

The captioned compound was synthesized from 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acid obtained in step B of Example 2-2-1 and 2-amino-1,3-propanediol in accordance with the same procedure as in the methods described in step C of Example 1-2-3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705053B2
Source datasetuspto-grants-2010_04
ORD IDord-13e6480e22bf462bb325ab68b7b92fad
Source noteuspto-grants-2010_04