HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-amino-3-(tert-butoxy)propanoic acid → (S)-3-t-butoxy-2-{4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoylamino}propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-amino-3-(tert-butoxy)propanoic acid | HCID 7004940 | — |
| Reactant | 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acid | HCID 23141498 | — |
| Product | (S)-3-t-butoxy-2-{4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoylamino}propionic acid | HCID 67002188 | — |
Reaction Steps
The (S)-3-t-butoxy-2-{4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoylamino}propionic acid was synthesized from 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acid obtained in step B of Example 2-2-1 and O-t-butyl-L-serine in accordance with the same procedure as in the methods described in step C of Example 1-2-3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705053B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-8c79d5253f3d41d7be1b4065ad7e3dcf |
| Source note | uspto-grants-2010_04 |