HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzo[b]furan-2-boronic acid → (4-Benzofuran-2-yl-phenyl)-((S)-2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzo[b]furan-2-boronic acid | HCID 2776266 | — |
| Reactant | (4-Bromo-phenyl)-(2-pyrrolidin-1-ylmethyl-pyrrolidin-yl)methanone | HCID 11964813 | — |
| Product | (4-Benzofuran-2-yl-phenyl)-((S)-2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone | HCID 68545718 | — |
Reaction Steps
The title compound is prepared in a manner substantially analogous to Procedure Q starting from 2-Benzofuran boronic acid and 4-(2-Pyrrolidin-1-ylmethyl-pyrrolidine-1-carbonyl)-phenyl bromide to give 52 mg (47%). MS (ES+) 375.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705025B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-85b17540f59c4db085025727c8cb18db |
| Source note | uspto-grants-2010_04 |