1-[(5-Bromo-2-thienyl)carbonyl]pyrrolidine → [2-(S)-(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-{4-[5-(pyrrolidine-1-carbonyl)-thiophen-2-yl]-phenyl}-methanone

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The title compound is prepared in a manner substantially analogous to General Procedure A using [2-(S)-(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-methanone (398 mg, 1.0 mmol) and (5-Bromo-thiophen-2-yl)-pyrrolidin-1-yl-methanone (CAS 326875-64-3) 261 mg, 1.0 mmol) to give 150 mg (34% yield). MS (ES+) 452.2 (M+H)+

Provenance & Evidence