HRID646447

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C[C@@H]1CCCN1C[C@@H]1CCCN1C(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1F

HCID57980040

未命名化合物

HCID59174085

未命名化合物

PRODUCTS

生成物

结构：C[C@@H]1CCCN1C[C@@H]1CCCN1C(=O)c1ccc(-c2ncc(C(=O)N3CCCC3)s2)cc1F

HCID59264679

未命名化合物

收率 32%

PROCEDURE

实验过程

The title compound is prepared in a manner substantially analogous to General Procedure A using [2-Fluoro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl[2-(S)-(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone (354 mg, 0.85 mmol) and (2-bromo-thiazol-5-yl)-pyrrolidin-1-yl-methanone (222 mg, 0.85 mmol) to give 130 mg (32% yield). MS (ES+) 471.3 (M+H)+

WORKUP

后处理

customto give 130 mg (32% yield)