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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 646559Erstellt: 25. Oktober 2026

Isopropenylacetylene → 2-Isopropenyl-1-methanesulfonyl-5-nitro-6-trifluoromethyl-1H-indole

https://huagongshe.com/reaction/646559

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktIsopropenylacetyleneHCID 62323—
EduktN-[2-Iodo-4-nitro-5-(trifluoromethyl)phenyl]methanesulfonamideHCID 58979620—
Produkt2-Isopropenyl-1-methanesulfonyl-5-nitro-6-trifluoromethyl-1H-indoleHCID 58979592—

Reaktionsschritte

This compound was prepared using the general Sonagashira conditions as described in general Example C, starting from N-(2-iodo-4-nitro-5-trifluoromethyl-phenyl)-methanesulfonamide (9.0 g, 21.9 mmol) and 2-methyl-1-buten-3-yne (6.25 mL, 65.7 mmol) to yield the title compound as a reddish-brown solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07705147B2
Quelldatensatzuspto-grants-2010_04
ORD IDord-517d3eee5a5449fdb8b6bc698e8009fe
Quellennotizuspto-grants-2010_04