HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Isopropenylacetylene → 2-Isopropenyl-1-methanesulfonyl-5-nitro-6-trifluoromethyl-1H-indole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Isopropenylacetylene | HCID 62323 | — |
| Edukt | N-[2-Iodo-4-nitro-5-(trifluoromethyl)phenyl]methanesulfonamide | HCID 58979620 | — |
| Produkt | 2-Isopropenyl-1-methanesulfonyl-5-nitro-6-trifluoromethyl-1H-indole | HCID 58979592 | — |
Reaktionsschritte
This compound was prepared using the general Sonagashira conditions as described in general Example C, starting from N-(2-iodo-4-nitro-5-trifluoromethyl-phenyl)-methanesulfonamide (9.0 g, 21.9 mmol) and 2-methyl-1-buten-3-yne (6.25 mL, 65.7 mmol) to yield the title compound as a reddish-brown solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07705147B2 |
| Quelldatensatz | uspto-grants-2010_04 |
| ORD ID | ord-517d3eee5a5449fdb8b6bc698e8009fe |
| Quellennotiz | uspto-grants-2010_04 |