HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 6,6-Difluorohex-5-enoic acid chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 6,6-difluorohex-5-enoic Acid | HCID 11298056 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 6,6-Difluorohex-5-enoic acid chloride | HCID 19793839 | — |
Reaction Steps
10.23 ml (140.68 mmol) Thionyl chloride was added dropwise to 8.0 g (52.29 mmol) of the product of Example 9 at room temperature. A drop of dimethylformamide was added and the mixture heated under reflux for 6 hours. It was then distilled under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05248810 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-d30cf53005b044ea9db9fca6b67dce41 |
| Source note | uspto-grants-1993_09 |