反应详情

A solution of 3.59 g (11.28 mmol) 6,6-difluoro-5-trifluoromethyl-1-tert-butylsilyloxy-5-hexene in 50 ml methanol was treated with a teaspoon full of ion exchange resin and the mixture stirred for 3 hours at room temperature. The ion exchange resin was then filtered off and washed with methanol. The filtrate was carefully concentrated in a rotary evaporator (bath temperature=35° C.; 200 mbar). The residue was used without further purification.

1. filtrationThe ion exchange resin was then filtered off
2. washwashed with methanol
3. concentrationThe filtrate was carefully concentrated in a rotary evaporator (bath temperature=35° C.; 200 mbar)
4. customThe residue was used without further purification