Chloroacetic Acid → HCID 86739047, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 5-phenylamino-1,2-dithiol-3-thione (9 g), chloroacetic acid (4.15 g) and sodium iodide (6.6 g) in acetone (135 cc) is heated under reflux for 35 minutes. After cooling to a temperature of about 20° C., the insoluble product is filtered off and washed successively with acetone (3×15 cc), with water (3×10 cc) and then with acetone (3×10 cc). By recrystallisation of this crude product from methanol (470 cc), (3-phenylimino-1,2-dithiol-5-ylthio)-acetic acid hydroiodide (7.1 g) is obtained, melting at about 205° C. with decomposition.

Provenance & Evidence