Phosgene → 5-(4-Amino-3,5-dichlorophenyl)-3-(prop-2-en-1-yl)-1,3-oxazolidin-2-one

HRID 647146Notes

Reaction equation

[CH2:1]([NH:4][CH2:5][CH:6]([OH:16])[C:7]1[CH:12]=[C:11]([Cl:13])[C:10]([NH2:14])=[C:9]([Cl:15])[CH:8]=1)[CH:2]=[CH2:3].[C:17](Cl)(Cl)=[O:18]>>[NH2:14][C:10]1[C:11]([Cl:13])=[CH:12][C:7]([CH:6]2[O:16][C:17](=[O:18])[N:4]([CH2:1][CH:2]=[CH2:3])[CH2:5]2)=[CH:8][C:9]=1[Cl:15]

Participants

Reactant 2

HCID 6371Phosgene

HCID 54079094HCID 54079094, compound

Product 1

HCID 201344905-(4-Amino-3,5-dichlorophenyl)-3-(prop-2-en-1-yl)-1,3-oxazolidin-2-one

Procedure

In the same manner, α-[(allylamino)methyl]-4-amino-3,5-dichlorobenzyl alcohol is allowed to react with phosgene to afford 5-(4-amino-3,5-dichlorophenyl)-3-allyl-2-oxazolidinone.

Sources & evidence

ORD record: ord-9287c3b4eb594f0a8e66a813faf46c79
Source dataset: uspto-grants-1983_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04407819

Reaction notes

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