Formaldehyde → 3-(3-tert-Butyl-1,3-oxazolidin-5-yl)phenol

HRID 647153Notes

Reaction equation

HRID 647153 reaction equation
C([O:8][C:9]1[CH:10]=[C:11]([CH:20]=[CH:21][CH:22]=1)[CH:12]([OH:19])[CH2:13][NH:14][C:15]([CH3:18])([CH3:17])[CH3:16])C1C=CC=CC=1.[CH2:23]=O>>[OH:8][C:9]1[CH:10]=[C:11]([CH:12]2[O:19][CH2:23][N:14]([C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:13]2)[CH:20]=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 712FormaldehydeHCID 54151805HCID 54151805, compound

Product 1

HCID 201344783-(3-tert-Butyl-1,3-oxazolidin-5-yl)phenol

Procedure

In the manner described in Example 32, m-(Benzyloxy)-α-[(tert-butylamino)methyl]benzyl alcohol is reacted with formaldehyde to afford the oxazolidine derivative, which is debenzylated by the procedure of Example 28 to give the title compound.

Sources & evidence

ORD record
ord-40ea1a3d2caf4d08a617cbdfed25505c
Source dataset
uspto-grants-1983_10
Patent number
US04407819

Reaction notes

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