beta-Maltose → Maltitol

HRID 647237Notes

Reaction equation

HRID 647237 reaction equation
[CH2:1]([OH:23])[C@H:2]1[O:7][C@H:6]([O:8][C@H:9]2[C@H:14]([OH:15])[C@@H:13]([OH:16])[C@H:12]([OH:17])[O:11][C@@H:10]2[CH2:18][OH:19])[C@H:5]([OH:20])[C@@H:4]([OH:21])[C@@H:3]1[OH:22].[H][H]>[Ni]>[CH2:1]([OH:23])[C@H:2]1[O:7][C@H:6]([O:8][C@@H:9]([C@H:14]([OH:15])[C@@H:13]([OH:16])[CH2:12][OH:17])[C@H:10]([OH:11])[CH2:18][OH:19])[C@H:5]([OH:20])[C@@H:4]([OH:21])[C@@H:3]1[OH:22]

Participants

4

Reactant 2

HCID 6255beta-MaltoseHCID 178418361HCID 178418361, compound

Product 1

HCID 493591Maltitol

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

A 50% aqueous solution of the highly-purified maltose was placed in an autoclave, and added with Raney nickel catalyst in an amount of 10%. Thereafter, the content was heated to 90°-125° C., and hydrogenation was effected at the temperature and a hydrogen pressure of 20-100 kg/cm2. After completion of the hydrogenation, the Raney nickel catalyst was removed, and the residual aqueous solution was purified by decolorization with activated carbon, and deionization with ion exchangers according to conventional methods, obtaining a highly-purified maltitol solution with a purity of 98.5%.

Workup

  1. temperatureThereafter, the content was heated to 90°-125° C.
  2. customAfter completion of the hydrogenation, the Raney nickel catalyst was removed
  3. customthe residual aqueous solution was purified by decolorization with activated carbon, and deionization with ion exchangers

Sources & evidence

ORD record
ord-3f566d3fb8514df48ce68c9447ab0414
Source dataset
uspto-grants-1983_10
Patent number
US04408041

Reaction notes

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