HCID 13269707, compound → HCID 13269713, compound

Participants

Reaction Steps

Following the procedures outlined in Example (2), the isomer mixture of (±) 4-acetamido-5-chloro-2-methoxy-N-(1'-quinolizidinyl-methyl)-benzamide (4.0 g) was converted to the crude product. Chromatography on Brockman II basic alumina (200 g), using methylene chloride as eluant, afforded one of the isomers (A, 0.9 g, 15%) of (±) 4-amino-5-chloro-2-methoxy-N-(1'-quinolizidinyl-methyl)-benzamide mp 155°-6°.

Provenance & Evidence