HCID 178478164, compound → HCID 178515473, compound

HRID 647518Notes

Reaction equation

HRID 647518 reaction equation
[Cl-:1].C([O:9][C:10]1[CH:18]=[CH:17][C:16]2[C:12](=[CH:13][N:14]3[CH2:21][CH2:20][CH2:19][N+:15]3=2)[CH:11]=1)C1C=CC=CC=1>CO.[Pd]>[Cl-:1].[OH:9][C:10]1[CH:18]=[CH:17][C:16]2[C:12](=[CH:13][N:14]3[CH2:21][CH2:20][CH2:19][N+:15]3=2)[CH:11]=1

Participants

4

Reactant 1

HCID 178478164HCID 178478164, compound

Product 1

HCID 178515473HCID 178515473, compoundYield 83.3%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

2,3-Dihydro-7-benzyloxy-1H-pyrazolo[1,2-a]indazolium chloride (6 g) obtained in Examples 1 and 2 was dissolved in methanol (100 ml) and catalytically reduced by adding 10% palladium-charcoal (0.6 g) to the solution, to give 3.5 g of 2,3-dihydro-7-hydroxy-1H-pyrazolo[1,2-a]indazolium chloride. After recrystallization from isobutanol, the product had a melting point of 278° to 279° C. (decomposition).

Sources & evidence

ORD record
ord-8d41aa43f3d84fd5b887587296ecb23f
Source dataset
uspto-grants-1983_10
Patent number
US04409234

Reaction notes

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